Completely revised and updated, and for the first time in stunning full-color, Bacterial Pathogenesis: A Molecular Approach, Fourth Edition, builds on the core principles and foundations of its predecessors while expanding into new concepts, key findings, and cutting-edge research, including new developments in the areas of the microbiome and CRISPR as well as the growing challenges of antimicrobial resistance. All-new detailed illustrations help students clearly understand important concepts and mechanisms of the complex interplay between bacterial pathogens and their hosts. Study questions at the end of each chapter challenge students to delve more deeply into the topics covered, and hone their skills in reading, interpreting, and analyzing data, as well as devising their own experiments.  A detailed glossary defines and expands on key terms highlighted throughout the book. Written for advanced undergraduate, graduate, and professional students in microbiology, bacteriology, and pathogenesis, this text is a must-have for anyone looking for a greater understanding of virulence mechanisms across the breadth of bacterial pathogens.

CHAPTER 1 The Power of Bacteria
CHAPTER 2 Skin and Mucosa: The First Lines of Defense against
CHAPTER 3 The Innate Immune System: Always on Guard
CHAPTER 4 The Adaptive Defenses: Antibodies and Cytotoxic T Cells
CHAPTER 5 The Microbiota of the Human Body: Microbiomes and Beyond
CHAPTER 6 Microbes and Disease: Establishing a Connection
CHAPTER 7 Mechanisms of Genetic Modification and Exchange: Role in Pathogen Evolution
CHAPTER 8 Identification of Virulence Factors: Measuring Infectivity and Virulence
CHAPTER 9 Identification of Virulence Factors: Molecular Approaches for Bacterial Factors
CHAPTER 10 Identification of Virulence Factors: Molecular Approaches for Host Factors
CHAPTER 11 Bacterial Strategies for Colonization and Survival in the Host
CHAPTER 12 Toxins and Other Toxic Virulence Factors
CHAPTER 13 Delivery of Virulence Factors
CHAPTER 14 Virulence Regulation
CHAPTER 15 Antimicrobial Compounds and Their Targets
CHAPTER 16 Antibiotic Resistance
CHAPTER 17 Vaccination: A Critical Component of the Modern Medical Armamentarium
CHAPTER 18 The Gram-Positive Opportunistic Pathogens
CHAPTER 19 The Gram-Negative Opportunistic Pathogens
CHAPTER 20 The Changing Roles of Microbiologists in an Age of Bioterrorism and Emerging Diseases